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"It is difficult to believe that until approximately year 1900 it was not known that neurons are the basic units of the brain (Santiago Ram? Equally surprising is the fact that the concept of chemical transmission in the brain was not known until around 1930 (Henry Hallett Dale) and (Otto Loewi).We began to understand the basic electrical phenomenon that neurons use in order to communicate among themselves, the action potential, in the decade of 1950 (Alan Lloyd Hodgkin, Andrew Huxley and John Eccles).The nervous system derives its name from nerves, which are cylindrical bundles of fibers (the axons of neurons), that emanate from the brain and spinal cord, and branch repeatedly to innervate every part of the body.Nerves are large enough to have been recognized by the ancient Egyptians, Greeks, and Romans, but their internal structure was not understood until it became possible to examine them using a microscope.There is an anatomical convention that a cluster of neurons in the brain or spinal cord is called a nucleus, whereas a cluster of neurons in the periphery is called a ganglion.There are, however, a few exceptions to this rule, notably including the part of the forebrain called the basal ganglia Arthropods, such as insects and crustaceans, have a nervous system made up of a series of ganglia, connected by a ventral nerve cord made up of two parallel connectives running along the length of the belly.

The PNS is divided into a) somatic and b) autonomic nervous system, and c) the enteric nervous system. The autonomic nervous system is further subdivided into the sympathetic and the parasympathetic nervous systems.The sensory information from these organs is processed by the brain.In insects, many neurons have cell bodies that are positioned at the edge of the brain and are electrically passive—the cell bodies serve only to provide metabolic support and do not participate in signalling.The neurons that give rise to nerves do not lie entirely within the nerves themselves—their cell bodies reside within the brain, spinal cord, or peripheral ganglia Glial cells (named from the Greek for "glue") are non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.

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In the human brain, it is estimated that the total number of glia roughly equals the number of neurons, although the proportions vary in different brain areas.

Typically, each body segment has one ganglion on each side, though some ganglia are fused to form the brain and other large ganglia.

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